Decision tree for NMA using aggregate and individual participant RWD

The following decision tree takes users who may be considering performing network meta-analysis (NMA) using real-world data (RWD) through a series of questions to determine the methods that should be used (assuming that the network is connected).

Figure. Decision tree for conducting a NMA including aggregate and individual participant RWD (assuming that the network is connected)

Decision tree for conducting a NMA

Abbreviations: IPD, individual participant data; NMA, network meta-analysis; NRS, non-randomised studies