Investigate and identify potential drivers of effectiveness for a medicine early in the medicine development process. This may highlight the need for different sources of evidence to demonstrate effectiveness.
Several methods may be used, separately or in combination, to identify important drivers of effectiveness:
- liaising with clinical experts – see Liaising with Clinical Experts
- conducting a literature review – see Conducting a Literature Review
- analysing existing randomised controlled trial and real-world data – see Analysing Existing Data